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Nutramax Denamarin Liver Health Supplement for Small Dogs and Cats - With S-Adenosylmethionine (SAMe) and Silybin, 30 Tablets
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Brand | Nutramax Laboratories |
Flavor | Liver |
Item Form | Tablet |
Active Ingredients | S-Adenosylmethionine 90 mg, Silybin-phosphatidylcholine complex (SPC)* 31 mg, *Providing 9 mg of Silybin A+B See more |
Item Weight | 9.98 Grams |
About this item
- Liver Support for Dogs and Cats: Denamarin is the #1 veterinarian recommended liver support supplement for dogs and cats. This supplement contains s-adenosylmethionine (SAMe) to help increase levels of the antioxidant glutathione - one of the liver’s main detoxifying agents
- High-Quality Ingredients: The Silybin found in Denamarin has shown better absorption by dogs and cats than the standardized milk thistle extract found in many other products
- Support Your Dog and Cat's Liver Health: The liver is one of the most vital organs in your pet and is responsible for removing toxins, storing energy, aiding digestion, and supporting the immune system
- From the #1 Veterinarian Recommended Supplement Company*: Nutramax Laboratories Veterinary Sciences has been a leader in pet health for over 30 years, and provides supplements to support joint health, digestive health, and overall wellness
- Backed by Science: Nutramax Laboratories Veterinary Sciences supplements are veterinarian formulated with high-quality ingredients to ensure your pet is receiving a safe supplement
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Price | $32.99$32.99 | -26% $19.90$19.90 List: $26.90 | $24.90$24.90 | $39.99$39.99 | -27% $26.99$26.99 List: $36.99 | $28.95$28.95 |
Delivery | Get it as soon as Monday, Apr 1 | Get it as soon as Monday, Apr 1 | Get it as soon as Monday, Apr 1 | Get it as soon as Monday, Apr 1 | Get it as soon as Monday, Apr 1 | Get it as soon as Monday, Apr 1 |
Customer Ratings | ||||||
Value for money | 4.1 | 4.7 | 4.2 | 3.5 | — | 5.0 |
Flavor | 3.7 | 4.0 | 4.1 | 3.6 | — | 4.0 |
Easy to use | 3.8 | — | 4.2 | 3.6 | — | 5.0 |
Sold By | Amazon.com | VITA PET LIFE | VITA PET LIFE | 1Family 1Health | BestLife4Pets | Fera Pet Organics |
flavor | Liver | Liver | Bacon and Liver | Liver, Bacon | Unflavored | Chicken Bone Broth |
form | Tablet | Tablet | Tablet | Tablet | Tablet | Powder |
active ingredients | S-Adenosylmethionine 90 mg, Silybin-phosphatidylcholine complex (SPC)* 31 mg, *Providing 9 mg of Silybin A+B | — | — | S-Adenosylmethionine(SAMe), Silybin- Phosphatidylcholine Complex (SPC), Silybin A+B, L Glutathione | — | Vitamin C (As Ascorbic Acid), Vitamin E, (D-Alpha Tocopherol), Zinc, Milk Thistle Seed Extract 80% Silymarin, Turmeric Root Extract Curcumin C3 Complex, N-Acetyl-L-Cysteine (NAC), Choline, N,N Dimethyl Glycine (DMG), Organic Artichoke Leaf, Organic Burdock Root, Organic Dandelion Root, Bioperine Black Pepper Extract |
size | Blister Pack Small Dog/Cat (under 12lbs) | Small Dogs (Under 14 lbs) | 120 Tablets | Small - Medium | — | 72g |
weight | 0.02 pounds | 14 pounds | 4 ounces | — | 2 ounces | 2.5 ounces |
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Product details
- Is Discontinued By Manufacturer : No
- Item model number : DENAMARIN90
- Date First Available : January 25, 2008
- Manufacturer : Nutramax Laboratories Veterinary Sciences, Inc.
- ASIN : B0011XHGQ6
- Country of Origin : USA
- Best Sellers Rank: #283 in Pet Supplies (See Top 100 in Pet Supplies)
- Customer Reviews:
Product Description
Denamarin coated tablets containing SAMe (s-adenosylmethionine) and silybin can be used in dogs and cats of all sizes to help support healthy liver functions. In addition, research has shown the administration of Denamarin coated tablets to be safe for dogs and cats. Denamarin Liver Health Supplements are brought to you by Nutramax Laboratories Veterinary Sciences, the #1 veterinarian recommended supplement company. *Source: Survey conducted among small animal veterinarians who recommended animal supplements.
Important information
Ingredients
S-Adenosylmethionine (90 mg)and Silybin-phosphatidylcholine (SPC, 31 mg) providing Silybin A+B (9 mg)
Directions
For dogs 35 - 65 lbs, 1 tablet per day, for dogs 66 - 120 lbs, 2 tablets per day, and for dogs over 120 lbs, 3 tablets per day. Tablets should be given on an empty stomach for optimal absorption. They may be given at least two hours after a meal or one hour before a meal.
Customer reviews
Customer Reviews, including Product Star Ratings help customers to learn more about the product and decide whether it is the right product for them.
To calculate the overall star rating and percentage breakdown by star, we don’t use a simple average. Instead, our system considers things like how recent a review is and if the reviewer bought the item on Amazon. It also analyzed reviews to verify trustworthiness.
Learn more how customers reviews work on AmazonCustomers say
Customers like the liver support of the animal nutritional supplement. They say it helps improve liver health and function. They also say it relieves pain and stress symptoms in dogs. They find the product easy to administer and dispense. Customers are happy with the quality and liver function. However, some customers have concerns about the size of the pill. They mention it's a big and bulky pill for a small dog. Customers disagree on taste and value.
AI-generated from the text of customer reviews
Customers are satisfied with the quality of the animal nutritional supplement. They say it's amazing, a worthwhile addition to the supplemental diet of old dogs, and has great benefits. Some mention that the savings are good by buying the product here. Overall, most are happy with their purchase and recommend it to others.
"...the conditions that I have stipulated, this is a worthwhile addition to the supplemental diet of old dogs." Read more
"...These can be a mid-day snack, or actually a small meal if we are out hiking, etc...." Read more
"These work good on our dog." Read more
"This is an amazing product. I use it with a pill popper tool I got at the vet...." Read more
Customers are happy with the liver support. They say it helps improve liver health, cures liver problems, and maintains good liver function. Some customers say it magically lowered bad liver numbers within a few days. Overall, customers are satisfied with the product's effectiveness.
"...This is a nom-prescription item that magically lowered bad liver numbers, sometimes within a three or four week period.. It is very expensive, but..." Read more
"...I would give 5 stars otherwise! This has helped my cat with his liver enzymes tremendously, & priced better than my local vet." Read more
"...The test results have improved significantly, but I’m not sure that it’s only because of these pills, because we have been prescribed a lot of..." Read more
"...She is on her 9th pill today and so far no side effects...." Read more
Customers like the pain relief of the animal nutritional supplement. They say it helps their old dog feel better, is more playful, and relaxed with stressful situations. They also say it makes their life easier and does not cause stomach upset. Customers also mention that the pills are not so cranky.
"...But, it is effective on many dogs. And that is a miracle for me...." Read more
"Give them good liver health and more energy, they look more active better." Read more
"Recommended by vet. Has helped our old dog feel better." Read more
"...Eating throughout this has been difficult. Turning down filet mignon or whatever concoction I could come up with to tempt him to eat...." Read more
Customers find the animal nutritional supplement easy to use. They say it's easy to administer, give, and dispense. Customers also appreciate the veterinary approval and the fact that it doesn't require a prescription. They mention that the coated pills go down easily.
"...So much cheaper, received much quicker, and easier to dispense from bottle. Have saved a lot of money with the subscribe and save!" Read more
"...Giving these pills is simple, as long as you’re good at molding cheese/bread coverings or have pill pockets...." Read more
"...There are very specific directions to follow when administering these tablets that must be followed, or the tabs will be useless...." Read more
"...The margerine makes the pill slide down easily & w/out any fuss. It's gone in literally a nanosecond!..." Read more
Customers like the liver function of the animal nutritional supplement. They say that it works, and their liver values keep getting better. Some customers also mention that their blood levels and health greatly improved after taking the product.
"...to use NSAID's in conjunction with Denemarin, and the liver numbers are far better, and the dogs are not doped-up on narcotics, but can enjoy their..." Read more
"...function tested several times since he started these and the levels have been perfect with the exception of one slight elevation that is to be..." Read more
"...It's been 3 months and the results are in. The liver levels are back to normal...." Read more
"...this is the direct result of the supplements, I can say that his numbers are great...." Read more
Customers are mixed about the value of the animal nutritional supplement. Some mention that it's affordable, while others say that it is expensive. The pills are not cheap, but the price is considerably cheaper than the vets price. However, some customers mention that the contents are rendered useless if exposed to air for more than a few hours.
"Purchased with vet recommendation, great on-line price. Loves the flavor." Read more
"...Again, it is expensive, this makes for a very hard decision for every pet lover. But, it is effective on many dogs. And that is a miracle for me...." Read more
"While I appreciate the product for working (& the cheaper price here versus the vet)..." Read more
"...product to my dog every day after recommendation from vet, costs a fraction of the price of what the vet wants...." Read more
Customers are mixed about the taste of the animal nutritional supplement. Some mention that they love the taste, it goes down easy with coating, and does not have any added flavors. However, others say that it has a nasty taste, is not very palatable, and the coating tastes unpleasant.
"...These miracle NSAID's were pretty rough on the livers of the old dogs...." Read more
"...The Vetri-liver isn't extremely palatable, but I just cut it in pieces and put it in meat or cheese, and it will go down...." Read more
"Purchased with vet recommendation, great on-line price. Loves the flavor." Read more
"...get her to take them, she would start foaming at the mouth from the nasty taste...." Read more
Customers are dissatisfied with the size of the animal nutritional supplement. They mention that it's pretty big, extremely large tablets, and bulky. Some say that the pill is huge for a small dog and that they don't recommend breaking it.
"...I don't know but I am a fan. The pills were not as small as one could hope (cats not being that easy to pill) but with a "pill popper" to get it..." Read more
"These pills are gigantic. It is a daily struggle to feed one to my dog...." Read more
"very small tablets, very convenient to put in a tasty treat...." Read more
"...My dog never takes pills easily. These are huge. She is 35 lbs. She can smell meds a mile away...." Read more
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The problem was that the old dogs all had arthritis, many had been brutalized and abandoned by previous owners, and there were some things that could not be fixed. However, finally we had access to a wide canine assortment of NSAID's. This was wonderful, the previous only hope was aspirin, with many associated bleeding risks, or dangerous steroids for their poor inflamed, badly healed, and otherwise painful limbs. They were always so good, even though I knew that they were suffering.
Then, we suddenly had access to the wonderful mom-steroidal pain relievers. This was magic stuff. Dogs that could barely walk were bouncing around, dogs that could not climb stairs were bounding up, two steps at a time. However, there was a dark side to all of this joy...as we soon discovered. These miracle NSAID's were pretty rough on the livers of the old dogs. So much so that I was faced with the awful choice of continuing that medication, knowing that it was destroying their liver, but it was also keeping the dogs joints pain-free. My other alternative was no good alternative - no NSAIDS, just heavier and heavier doses of narcotics for the pain......helplessly watching the failing test results of my poor old pups.
I lost quite a few that way, it almost killed me. Then Denamarin, and Marin came along. I use both on my old pups and it is another miraculous thing to witness. This is a nom-prescription item that magically lowered bad liver numbers, sometimes within a three or four week period.. It is very expensive, but Amazon has the best price of all.
My dogs are living now, and not teetering on the edge with failing livers. It is possible to use NSAID's in conjunction with Denemarin, and the liver numbers are far better, and the dogs are not doped-up on narcotics, but can enjoy their last days. I am amazed by the breakthroughs that I have witnessed in the veterinary world over the last ten years that I have been fostering. Sometimes it is pretty magical, old dogs frolicking around my ankles each morning, demanding a treat, just like a bunch of pups.
I am not a vet., I wish to make that crystal clea. I have no connection whatsoever with this company, indeed had never heard of them before my vet mentioned this drug. All that I can say is that I have had dogs my entire life, and I have witnessed far too many agonizing decisions that have had to be made. Watching an agonized old dog, painfully hobble around, or give the drug that will help with the arthritis...and have very negative effects with their livers. In the.end, we usually just tried to keep them out of pain, but they had.no good quality of life.
Again, to be perfectly clear, with MY old dogs, under MY care, eating the very best of dog kibble, no fatty treats, no people food, and someone around at all times to give the drugs at the appropriate times, I have seen rapidly discernible improvement in my older guys. Not every dog reacts the same way, doses can be tricky, and.require a lot of blood testing' and fiddling with dosages, my dogs have definitely improved. Not all have a glorious outcome. But If they are willing to get out of their beds, and follow me to the kitchen to beg for food, my heart is happy. When you are working with old, injured, and sick dogs...little things matter a lot.
Denemarin, along with another supplement : Marin, have made the lives of some of the older fur kids better, and happier. This will not save your old dog, there will be heart problems, cancers, and other issues upon which Denemarin has no effect. But for the dogs in the specific conditions that I have outlined, I have seen a definite difference in both the quality of life for the dog, as well as better liver readings on their blood tests.
Again, it is expensive, this makes for a very hard decision for every pet lover. But, it is effective on many dogs. And that is a miracle for me. We are saving dogs that we would have lost ten years ago, and this supplement has had a lot to do with that.
It is up to the pet owner, but under the conditions that I have stipulated, this is a worthwhile addition to the supplemental diet of old dogs.
My story: Our dog is a 12ish Jack Russell mix. In August 2017, he was off. Not himself. Bloodwork and ultrasound showed he likely had Chronic Hepatitis. Put him on Denamarin. Bloodwork improved, but still not perfect. Had the vet do a dental thinking that the liver issues could be from bad teeth. They put him on a preventative antibiotic. 1 week after the Dental he spiked a 106 fever. He was ultimately put on IVs with a different antibiotic. Fever came down, felt better. Noticed that he had developed a licking issue after eating which was new. Fever slowly started to climb back upward. At 104 he was put back on IVs, taken off of all antibiotics in an attempt to get the bacteria to flourish and to isolate it. The only problem was that once he was off of the antibiotics his temperature went normal never to return. Eating throughout this has been difficult. Turning down filet mignon or whatever concoction I could come up with to tempt him to eat. I had pointed out to the vets (lots of them) that the antibiotics warned against liver and kidney issues. Everyone poo poo'd that. Well, it turns out that his liver couldn't process them.
I took him home on Christmas Day from the vet hospital. They wanted to do a liver biopsy, but I rejected it. He already looked like warmed over death. Wasn't eating a thing in the hospital. They would have had to put him back on antibiotics. - And there was no clear indication that the liver was the origin of the problem, and could just be a secondary to another issue like heart disease (he does have a small heart murmur, but his heart is working sufficiently), cancer, etc. Even if we knew exactly what the liver diagnosis was, the treatment wouldn't be much different: Diet, supplements and potentially prednisone (which is hard on the liver as well - catch 22)
At home, he was a new dog. He started eating. I researched every liver diet, and started with a very bland, home-cooked meal. I noticed that if I added a hi-end kibble to his diet, there would be more licking (licking surfaces like the carpeting). I read where compulsive licking is often intestinal distress. I'm not convinced that he also didn't have some kind of gastric issue, like gastric ulcers, or other intestinal issue, perhaps because of the liver or maybe even driving the liver problem.
It is the end of April 2018, and he is doing well. I started him on Vetri-liver in the AM a couple of months ago with a breakfast of eggs, cottage cheese, oatmeal, rice, and chicken/turkey or beef). The Vetri-liver isn't extremely palatable, but I just cut it in pieces and put it in meat or cheese, and it will go down. Since I don't have a firm diagnosis for the liver problem, I looked for zinc and anti-oxidants to help the liver even if he had a copper retention problem. Zinc is supposed to offset copper in your diet. It also has some other supplements that he may need.
Afternoon, he gets his Denamarin tablet (2 hours after the last meal) and 1 hour before dinner.
Supposedly vegetable protein is better for dogs with liver disease. So I came up with some treats that also helped, especially in the beginning when getting him to eat was hard. I fill a turkey pan with: eggs, meat, carrots, sweet potatoes, tofu, wheat germ, peanut butter, coconut oil, and enough oats and a little bit of flour to make a cookie dough. The secret ingredient is a little bacon grease and bacon for palatability. Yes, bad, but makes the difference between this going down the hatch. These can be a mid-day snack, or actually a small meal if we are out hiking, etc. I bake them on cookie tins like brownies, cut them into squares, put them in baggies, and throw them in the freezer. This way they stay fresh.
Dinner is rice/oatmeal/sweet potatoes/pumpkin or yams mixed with eggs/chicken/turkey/beef along with some well-processed veggies.
I'm not convinced that I'm feeding a balanced diet, so I bought some senior dog vitamins that he gets periodically.
Slowly the weight is coming back on. Exercise is important, because he is hungry after exercise. So a small walk in the morning before breakfast and walk before dinner really makes a difference with the pills and food going down. As long as he is eating soft, smaller meals, the compulsive licking has stopped.
He is energetic, playing with toys, bright on his walks and back among the living. His liver enzymes are not perfect: ALT started at 275 (August 2017), went to 1,800 during the antibiotic reaction and spiked fever, back to 275 and now down to 253 most recently. ALP started at 263, 656 at its worst, and now at 167. I don't know if I will be successful in getting them to normal ranges, but if I look at his quality of life, it looks pretty good now.
I wanted to share my story, because you don't hear often that antibiotics could almost kill your dog. And.....your dog can come back after refusing to eat anything after dire illness.
Considering a backpack Trip!!
Reviewed in the United States on April 29, 2018
My story: Our dog is a 12ish Jack Russell mix. In August 2017, he was off. Not himself. Bloodwork and ultrasound showed he likely had Chronic Hepatitis. Put him on Denamarin. Bloodwork improved, but still not perfect. Had the vet do a dental thinking that the liver issues could be from bad teeth. They put him on a preventative antibiotic. 1 week after the Dental he spiked a 106 fever. He was ultimately put on IVs with a different antibiotic. Fever came down, felt better. Noticed that he had developed a licking issue after eating which was new. Fever slowly started to climb back upward. At 104 he was put back on IVs, taken off of all antibiotics in an attempt to get the bacteria to flourish and to isolate it. The only problem was that once he was off of the antibiotics his temperature went normal never to return. Eating throughout this has been difficult. Turning down filet mignon or whatever concoction I could come up with to tempt him to eat. I had pointed out to the vets (lots of them) that the antibiotics warned against liver and kidney issues. Everyone poo poo'd that. Well, it turns out that his liver couldn't process them.
I took him home on Christmas Day from the vet hospital. They wanted to do a liver biopsy, but I rejected it. He already looked like warmed over death. Wasn't eating a thing in the hospital. They would have had to put him back on antibiotics. - And there was no clear indication that the liver was the origin of the problem, and could just be a secondary to another issue like heart disease (he does have a small heart murmur, but his heart is working sufficiently), cancer, etc. Even if we knew exactly what the liver diagnosis was, the treatment wouldn't be much different: Diet, supplements and potentially prednisone (which is hard on the liver as well - catch 22)
At home, he was a new dog. He started eating. I researched every liver diet, and started with a very bland, home-cooked meal. I noticed that if I added a hi-end kibble to his diet, there would be more licking (licking surfaces like the carpeting). I read where compulsive licking is often intestinal distress. I'm not convinced that he also didn't have some kind of gastric issue, like gastric ulcers, or other intestinal issue, perhaps because of the liver or maybe even driving the liver problem.
It is the end of April 2018, and he is doing well. I started him on Vetri-liver in the AM a couple of months ago with a breakfast of eggs, cottage cheese, oatmeal, rice, and chicken/turkey or beef). The Vetri-liver isn't extremely palatable, but I just cut it in pieces and put it in meat or cheese, and it will go down. Since I don't have a firm diagnosis for the liver problem, I looked for zinc and anti-oxidants to help the liver even if he had a copper retention problem. Zinc is supposed to offset copper in your diet. It also has some other supplements that he may need.
Afternoon, he gets his Denamarin tablet (2 hours after the last meal) and 1 hour before dinner.
Supposedly vegetable protein is better for dogs with liver disease. So I came up with some treats that also helped, especially in the beginning when getting him to eat was hard. I fill a turkey pan with: eggs, meat, carrots, sweet potatoes, tofu, wheat germ, peanut butter, coconut oil, and enough oats and a little bit of flour to make a cookie dough. The secret ingredient is a little bacon grease and bacon for palatability. Yes, bad, but makes the difference between this going down the hatch. These can be a mid-day snack, or actually a small meal if we are out hiking, etc. I bake them on cookie tins like brownies, cut them into squares, put them in baggies, and throw them in the freezer. This way they stay fresh.
Dinner is rice/oatmeal/sweet potatoes/pumpkin or yams mixed with eggs/chicken/turkey/beef along with some well-processed veggies.
I'm not convinced that I'm feeding a balanced diet, so I bought some senior dog vitamins that he gets periodically.
Slowly the weight is coming back on. Exercise is important, because he is hungry after exercise. So a small walk in the morning before breakfast and walk before dinner really makes a difference with the pills and food going down. As long as he is eating soft, smaller meals, the compulsive licking has stopped.
He is energetic, playing with toys, bright on his walks and back among the living. His liver enzymes are not perfect: ALT started at 275 (August 2017), went to 1,800 during the antibiotic reaction and spiked fever, back to 275 and now down to 253 most recently. ALP started at 263, 656 at its worst, and now at 167. I don't know if I will be successful in getting them to normal ranges, but if I look at his quality of life, it looks pretty good now.
I wanted to share my story, because you don't hear often that antibiotics could almost kill your dog. And.....your dog can come back after refusing to eat anything after dire illness.
Considering a backpack Trip!!
It would be great for a version of this that could be crushed/edible/?, to make it easier to administer. My vet said it can’t even be crushed in this current form…
Many of the other reviews here echo this issue with pet rejection/taste, so this would be helpful to avoid stressful situations (for both owner & pet!).
The Greenies pill pockets were the only way I could get my cat to take to this medicine. Word of advice for the pill pockets: “To prevent transfer of the medicine’s smell and taste, do not touch the pill pockets treat with the hand that held the medicine” (from the manufacturer).
I would give 5 stars otherwise! This has helped my cat with his liver enzymes tremendously, & priced better than my local vet.
Reviewed in the United States on December 11, 2023
It would be great for a version of this that could be crushed/edible/?, to make it easier to administer. My vet said it can’t even be crushed in this current form…
Many of the other reviews here echo this issue with pet rejection/taste, so this would be helpful to avoid stressful situations (for both owner & pet!).
The Greenies pill pockets were the only way I could get my cat to take to this medicine. Word of advice for the pill pockets: “To prevent transfer of the medicine’s smell and taste, do not touch the pill pockets treat with the hand that held the medicine” (from the manufacturer).
I would give 5 stars otherwise! This has helped my cat with his liver enzymes tremendously, & priced better than my local vet.